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Selective delivery of interleukine-1 receptor antagonist to inflamed joint by albumin fusion

BACKGROUND: Interleukin-1 receptor antagonist, a cytokine that is highly therapeutic to rheumatoid arthritis and several other inflammatory diseases, exhibits rapid blood clearance and poor retention time on the target in clinical application due to its small size and lack of specificity to target t...

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Detalhes bibliográficos
Main Authors: Liu, Mengyuan, Huang, Yi, Hu, Lei, Liu, Guoping, Hu, Xueping, Liu, Dongxu, Yang, Xiaosong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505484/
https://ncbi.nlm.nih.gov/pubmed/23006786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-68
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