Persistent Signaling by Dysregulated Thrombin Receptor Trafficking Promotes Breast Carcinoma Cell Invasion

Increased expression of protease-activated receptor 1 (PAR1), a G protein-coupled receptor for thrombin, has previously been correlated with breast carcinoma cell invasion. PAR1 is irreversibly proteolytically activated, internalized, and sorted directly to lysosomes, a critical process for the term...

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Detaylı Bibliyografya
Asıl Yazarlar: Booden, Michelle A., Eckert, Lynn B., Der, Channing J., Trejo, JoAnn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2004
Konular:
Cell Growth and Development
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC350540/
https://ncbi.nlm.nih.gov/pubmed/14966279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.1990-1999.2004
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