Verapamil- and state-dependent effect of 2-aminoethylmethanethiosulphonate (MTSEA) on hK(v)1.3 channels

BACKGROUND AND PURPOSE: T-cells usually express voltage-gated K(v)1.3 channels. These channels are distinguished by their typical C-type inactivation. Therefore, to be able to rationally design drugs specific for the C-type inactivation state that may have therapeutic value in autoimmune disease the...

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Detalhes bibliográficos
Main Authors: Nikouee, Azadeh, Janbein, Malika, Grissmer, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505002/
https://ncbi.nlm.nih.gov/pubmed/22748056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02092.x
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