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Effect of K(+) and Rb(+) on the action of verapamil on a voltage-gated K(+) channel, hK(v)1.3: implications for a second open state?

BACKGROUND AND PURPOSE: Verapamil blocks current through the voltage-gated K(+) channel K(v)1.3 in the open and inactivated state of the channel but not the closed state. The binding site for verapamil was proposed to be close to the selectivity filter and the occupancy of the selectivity filter mig...

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Detalhes bibliográficos
Main Authors: Kuras, Z, Grissmer, S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721261/
https://ncbi.nlm.nih.gov/pubmed/19371328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00202.x
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