Tityustoxin-K(alpha) blockade of the voltage-gated potassium channel Kv1.3

1. We investigated the action of TsTX-Kα on cloned Kv1.3 channels of the Shaker subfamily of voltage-gated potassium channels, using the voltage–clamp technique. Highly purified TsTX-Kα was obtained from the venom of the Brazilian scorpion Tityus serrulatus using a new purification protocol. Our res...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rodrigues, Aldo Rogelis A, Arantes, Eliane C, Monje, Francisco, Stuhmer, Walter, Varanda, Wamberto Antonio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2003
Pynciau:
Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573937/
https://ncbi.nlm.nih.gov/pubmed/12871837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705343
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