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Kuppfer Cells Trigger Nonalcoholic Steatohepatitis Development in Diet-induced Mouse Model through Tumor Necrosis Factor-α Production

Nonalcoholic steatohepatitis (NASH), characterized by lipid deposits within hepatocytes (steatosis), is associated with hepatic injury and inflammation and leads to the development of fibrosis, cirrhosis, and hepatocarcinoma. However, the pathogenic mechanism of NASH is not well understood. To deter...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tosello-Trampont, Annie-Carole, Landes, Susan G., Nguyen, Virginia, Novobrantseva, Tatiana I., Hahn, Young S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504730/
https://ncbi.nlm.nih.gov/pubmed/23066023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.417014
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