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Kuppfer Cells Trigger Nonalcoholic Steatohepatitis Development in Diet-induced Mouse Model through Tumor Necrosis Factor-α Production

Nonalcoholic steatohepatitis (NASH), characterized by lipid deposits within hepatocytes (steatosis), is associated with hepatic injury and inflammation and leads to the development of fibrosis, cirrhosis, and hepatocarcinoma. However, the pathogenic mechanism of NASH is not well understood. To deter...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tosello-Trampont, Annie-Carole, Landes, Susan G., Nguyen, Virginia, Novobrantseva, Tatiana I., Hahn, Young S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504730/
https://ncbi.nlm.nih.gov/pubmed/23066023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.417014
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