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NKp46(+) NK cells attenuate metabolism-induced hepatic fibrosis by regulating macrophage activation

Non-alcoholic steatohepatitis (NASH) affects 3–5% of the U. S. population having severe clinical complications to the development of fibrosis and end-stage liver diseases such as cirrhosis and hepatocellular carcinoma. A critical cause of NASH is chronic systemic inflammation promoted by innate immu...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Tosello-Trampont, Annie-Carole, Krueger, Peter, Narayanan, Sowmya, Landes, Susan G., Leitinger, Norbert, Hahn, Young S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764418/
https://ncbi.nlm.nih.gov/pubmed/26662852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28389
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