Inhibition of polyadenylation reduces inflammatory gene induction

Cordycepin (3′ deoxyadenosine) has long been used in the study of in vitro assembled polyadenylation complexes, because it terminates the poly(A) tail and arrests the cleavage complex. It is derived from caterpillar fungi, which are highly prized in Chinese traditional medicine. Here we show that co...

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Hlavní autoři: Kondrashov, Alexander, Meijer, Hedda A., Barthet-Barateig, Adeline, Parker, Hannah N., Khurshid, Asma, Tessier, Sarah, Sicard, Marie, Knox, Alan J., Pang, Linhua, de Moor, Cornelia H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504674/
https://ncbi.nlm.nih.gov/pubmed/23118416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.032391.112
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