Inhibition of polyadenylation reduces inflammatory gene induction

Cordycepin (3′ deoxyadenosine) has long been used in the study of in vitro assembled polyadenylation complexes, because it terminates the poly(A) tail and arrests the cleavage complex. It is derived from caterpillar fungi, which are highly prized in Chinese traditional medicine. Here we show that co...

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Autores principales: Kondrashov, Alexander, Meijer, Hedda A., Barthet-Barateig, Adeline, Parker, Hannah N., Khurshid, Asma, Tessier, Sarah, Sicard, Marie, Knox, Alan J., Pang, Linhua, de Moor, Cornelia H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504674/
https://ncbi.nlm.nih.gov/pubmed/23118416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.032391.112
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