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RNase III-independent microRNA biogenesis in mammalian cells

RNase III enzymes are fundamental to the biogenesis of microRNAs (miRNAs) and small interfering RNAs (siRNAs) in all species studied. Although alternative miRNA pathways independent of Drosha or Dicer exist, each still requires one RNase III-type enzyme. Here, we describe two strategies that marry e...

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Bibliografske podrobnosti
Main Authors: Maurin, Thomas, Cazalla, Demián, Yang, Jr-Shiuan, Bortolamiol-Becet, Diane, Lai, Eric C.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504669/
https://ncbi.nlm.nih.gov/pubmed/23097423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.036194.112
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