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Oncogenes in Cell Survival and Cell Death
The transforming effects of proto-oncogenes such as MYC that mediate unrestrained cell proliferation are countered by “intrinsic tumor suppressor mechanisms” that most often trigger apoptosis. Therefore, cooperating genetic or epigenetic effects to suppress apoptosis (e.g., overexpression of BCL2) a...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504432/ https://ncbi.nlm.nih.gov/pubmed/23209150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a009829 |
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