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Hypoxia Activated EGFR Signaling Induces Epithelial to Mesenchymal Transition (EMT)

Metastasis is a multi-step process which requires the conversion of polarized epithelial cells to mesenchymal cells, Epithelial–Mesenchymal Transition (EMT). EMT is essential during embryonic morphogenesis and has been implicated in the progression of primary tumors towards metastasis. Hypoxia is kn...

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Detalles Bibliográficos
Autores principales: Misra, Ashish, Pandey, Chhiti, Sze, Siu Kwan, Thanabalu, Thirumaran
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504094/
https://ncbi.nlm.nih.gov/pubmed/23185433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049766
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