Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition (EMT)

RATIONALE: Many mechanically ventilated patients with acute respiratory distress syndrome (ARDS) develop pulmonary fibrosis. Stresses induced by mechanical ventilation may explain the development of fibrosis by a number of mechanisms (e.g. damage the alveolar epithelium, biotrauma). OBJECTIVES: To t...

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Vydáno v:Crit Care Med
Hlavní autoři: Cabrera-Benítez, Nuria E., Parotto, Matteo, Post, Martin, Han, Bing, Spieth, Peter M., Cheng, Wei-Erh, Valladares, Francisco, Villar, Jesús, Liu, Mingayo, Sato, Masaaki, Zhang, Haibo, Slutsky, Arthur S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5061566/
https://ncbi.nlm.nih.gov/pubmed/21926573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31822f09d7
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