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Hypoxia Activated EGFR Signaling Induces Epithelial to Mesenchymal Transition (EMT)

Metastasis is a multi-step process which requires the conversion of polarized epithelial cells to mesenchymal cells, Epithelial–Mesenchymal Transition (EMT). EMT is essential during embryonic morphogenesis and has been implicated in the progression of primary tumors towards metastasis. Hypoxia is kn...

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Detalhes bibliográficos
Main Authors: Misra, Ashish, Pandey, Chhiti, Sze, Siu Kwan, Thanabalu, Thirumaran
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504094/
https://ncbi.nlm.nih.gov/pubmed/23185433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049766
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