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Hypoxia Activated EGFR Signaling Induces Epithelial to Mesenchymal Transition (EMT)

Metastasis is a multi-step process which requires the conversion of polarized epithelial cells to mesenchymal cells, Epithelial–Mesenchymal Transition (EMT). EMT is essential during embryonic morphogenesis and has been implicated in the progression of primary tumors towards metastasis. Hypoxia is kn...

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Autors principals: Misra, Ashish, Pandey, Chhiti, Sze, Siu Kwan, Thanabalu, Thirumaran
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504094/
https://ncbi.nlm.nih.gov/pubmed/23185433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049766
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