Receptor-mediated internalization of fluorescent gonadotropin-releasing hormone by pituitary gonadotropes.

A bioactive, fluorescent derivative of gonadotropin-releasing hormone, < Glu-His-Trp-Ser-Tyr-D-Lys(N epsilon-tetramethylrhodamine)-Leu-Arg-Pro-Gly-NH2, was prepared. This peptide retained high-affinity binding (apparent dissociation constant, 3 nM) to the receptor for gonadotropin-releasing hormone...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hazum, E, Cuatrecasas, P, Marian, J, Conn, P M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1980
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350354/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6256756/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.11.6692
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