Receptor-mediated internalization of fluorescent gonadotropin-releasing hormone by pituitary gonadotropes.

A bioactive, fluorescent derivative of gonadotropin-releasing hormone, < Glu-His-Trp-Ser-Tyr-D-Lys(N epsilon-tetramethylrhodamine)-Leu-Arg-Pro-Gly-NH2, was prepared. This peptide retained high-affinity binding (apparent dissociation constant, 3 nM) to the receptor for gonadotropin-releasing hormo...

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Detalles Bibliográficos
Main Authors: Hazum, E, Cuatrecasas, P, Marian, J, Conn, P M
Formato: Artigo
Idioma:Inglês
Publicado: 1980
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC350354/
https://ncbi.nlm.nih.gov/pubmed/6256756
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