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Novel Cruzain Inhibitors for the Treatment of Chagas’ Disease

The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas’ disease, affects millions of individuals and continues to be an important global health concern. The poor efficacy and unfavorable side effects of current treatments necessitate novel therapeutics. Cruzain, the major cysteine...

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Detalhes bibliográficos
Main Authors: Rogers, Kathleen E, Keränen, Henrik, Durrant, Jacob D, Ratnam, Joseline, Doak, Allison, Arkin, Michelle R, McCammon, J Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503458/
https://ncbi.nlm.nih.gov/pubmed/22613098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2012.01416.x
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