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Computational Identification of Uncharacterized Cruzain Binding Sites

Chagas disease, caused by the unicellular parasite Trypanosoma cruzi, claims 50,000 lives annually and is the leading cause of infectious myocarditis in the world. As current antichagastic therapies like nifurtimox and benznidazole are highly toxic, ineffective at parasite eradication, and subject t...

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Detalhes bibliográficos
Main Authors: Durrant, Jacob D., Keränen, Henrik, Wilson, Benjamin A., McCammon, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867933/
https://ncbi.nlm.nih.gov/pubmed/20485483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000676
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