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TFIIB dephosphorylation links transcription inhibition with the p53-dependent DNA damage response

The general transcription factor II B (TFIIB) plays a central role in both the assembly of the transcription complex at gene promoters and also in the events that lead to transcription initiation. TFIIB is phosphorylated at serine-65 at the promoters of several endogenous genes, and this modificatio...

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Autori principali: Shandilya, Jayasha, Wang, Yuming, Roberts, Stefan G. E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503221/
https://ncbi.nlm.nih.gov/pubmed/23115335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207483109
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