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Conserved Region 3 of Human Papillomavirus 16 E7 Contributes to Deregulation of the Retinoblastoma Tumor Suppressor

The human papillomavirus (HPV) E7 oncoprotein binds cellular factors, preventing or retargeting their function and thereby making the infected cell conducive for viral replication. A key target of E7 is the product of the retinoblastoma susceptibility locus (pRb). This interaction results in the rel...

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Main Authors: Todorovic, Biljana, Hung, Katherine, Massimi, Paola, Avvakumov, Nikita, Dick, Frederick A., Shaw, Gary S., Banks, Lawrence, Mymryk, Joe S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503127/
https://ncbi.nlm.nih.gov/pubmed/23015707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01637-12
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