Conserved Region 3 of Human Papillomavirus 16 E7 Contributes to Deregulation of the Retinoblastoma Tumor Suppressor

The human papillomavirus (HPV) E7 oncoprotein binds cellular factors, preventing or retargeting their function and thereby making the infected cell conducive for viral replication. A key target of E7 is the product of the retinoblastoma susceptibility locus (pRb). This interaction results in the rel...

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Autori principali: Todorovic, Biljana, Hung, Katherine, Massimi, Paola, Avvakumov, Nikita, Dick, Frederick A., Shaw, Gary S., Banks, Lawrence, Mymryk, Joe S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503127/
https://ncbi.nlm.nih.gov/pubmed/23015707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01637-12
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