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Epitope-Specific CD8(+) T Cells Play a Differential Pathogenic Role in the Development of a Viral Disease Model for Multiple Sclerosis

Theiler's virus-induced demyelinating disease has been extensively investigated as a model for persistent viral infection and multiple sclerosis (MS). However, the role of CD8(+) T cells in the development of disease remains unclear. To assess the role of virus-specific CD8(+) T cells in the pa...

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Autores principales: Myoung, Jinjong, Kang, Hyun Seok, Hou, Wanqiu, Meng, Liping, Dal Canto, Mauro C., Kim, Byung S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503089/
https://ncbi.nlm.nih.gov/pubmed/23055563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01733-12
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