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A Spontaneous Low-Pathogenic Variant of Theiler’s Virus Contains an Amino Acid Substitution within the Predominant VP1(233–250) T-Cell Epitope

Theiler’s murine encephalomyelitis virus (TMEV) induces immune-mediated demyelination after intracerebral inoculation of the virus into susceptible mouse strains. We isolated from a TMEV BeAn 8386 viral stock, a low-pathogenic variant which requires greater than a 10,000-fold increase in viral inocu...

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書誌詳細
主要な著者: Kim, Byung S., Yauch, Robert L., Bahk, Young Yil, Kang, Jeong-Ah, Dal Canto, Mauro C., Hall, Catherine Kappel
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC124573/
https://ncbi.nlm.nih.gov/pubmed/9444995
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