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Severe Acute Respiratory Syndrome Coronavirus Protein nsp1 Is a Novel Eukaryotic Translation Inhibitor That Represses Multiple Steps of Translation Initiation

Severe acute respiratory syndrome (SARS) coronavirus nonstructural protein 1 (nsp1) binds to the 40S ribosomal subunit and inhibits translation, and it also induces a template-dependent endonucleolytic cleavage of host mRNAs. nsp1 inhibits the translation of cap-dependent and internal ribosome entry...

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Detaylı Bibliyografya
Asıl Yazarlar: Lokugamage, Kumari G., Narayanan, Krishna, Huang, Cheng, Makino, Shinji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503042/
https://ncbi.nlm.nih.gov/pubmed/23035226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01958-12
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