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Lapatinib and Obatoclax Kill Breast Cancer Cells through Reactive Oxygen Species-Dependent Endoplasmic Reticulum Stress

Previous studies showed that lapatinib and obatoclax interact in a greater-than-additive fashion to cause cell death and do so through a toxic form of autophagy. The present studies sought to extend our analyses. Lapatinib and obatoclax killed multiple tumor cell types, and cells lacking phosphatase...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cruickshanks, Nichola, Tang, Yong, Booth, Laurence, Hamed, Hossein, Grant, Steven, Dent, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502625/
https://ncbi.nlm.nih.gov/pubmed/22989520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.081539
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