Antifibrotic Effects of Roscovitine in Normal and Scleroderma Fibroblasts

Heightened production of collagen and other matrix proteins underlies the fibrotic phenotype of systemic sclerosis (SSc). Roscovitine is an inhibitor of cyclin-dependent kinases that promote cell cycling (CDK1, 2), neuronal development (CDK5) and control transcription (CDK7,9). In an in vivo glomeru...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Steinman, Richard A., Robinson, Andria Rasile, Feghali-Bostwick, Carol A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502367/
https://ncbi.nlm.nih.gov/pubmed/23185265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048560
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller