Characterization of antibody variants during process development: The tale of incomplete processing of N-terminal secretion peptide

Monoclonal antibodies (mAbs) have emerged as one of the most important classes of biotherapeutics, although development of these molecules is long and arduous. A production cell line must be established, and growth conditions for the cells and purification processes for the product must be optimized...

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Detaylı Bibliyografya
Asıl Yazarlar: Ambrogelly, Alexandre, Liu, Yan-Hui, Li, Hong, Mengisen, Selina, Yao, Bingyi, Xu, Wei, Cannon-Carlson, Susan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2012
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502237/
https://ncbi.nlm.nih.gov/pubmed/22932441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.21614
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