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“INTEGRINating” the connexin hemichannel function in bone osteocytes through the action of integrin α5

Mechanical loading influences skeletal structural integrity and bone remodeling. Application of a mechanical stimulus such as fluid flow shear stress to the bone osteocytes activates the cascade of mechanotransduction mediated by multiple signaling molecules. Hemichannels formed by connexin molecule...

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Bibliographic Details
Main Authors: Batra, Nidhi, Jiang, Jean X.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502221/
https://ncbi.nlm.nih.gov/pubmed/23739985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.21322
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