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Histone Deacetylase (HDAC) 1 Controls the Expression of Beta Defensin 1 in Human Lung Epithelial Cells

Deregulation of the expression human beta defensin 1 (DEFB1), an antimicrobial peptide, has been implicated in the pathogenesis of COPD and asthma. Since the molecular mechanisms that regulate DEFB1 gene expression are widely unknown, the epigenetic processes involved in the regulation of the consti...

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Detalhes bibliográficos
Main Authors: Kallsen, Kimberley, Andresen, Ellen, Heine, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502185/
https://ncbi.nlm.nih.gov/pubmed/23185513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050000
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