Induction of mitotic recombination in yeast by starvation for thymine nucleotides.

The biosynthesis of thymine nucleotides in Saccharomyces cerevisiae can be inhibited either by genetic lesions in the structural gene for thymidylate synthetase (TMP1) or by drugs that prevent the methylation of dUMP to dTMP. This methylation can be blocked by folate antagonists. We find that 5-fluo...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Kunz, B A, Barclay, B J, Game, J C, Little, J G, Haynes, R H
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1980
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6449701/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.10.6057
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