Induction of mitotic recombination in yeast by starvation for thymine nucleotides.
The biosynthesis of thymine nucleotides in Saccharomyces cerevisiae can be inhibited either by genetic lesions in the structural gene for thymidylate synthetase (TMP1) or by drugs that prevent the methylation of dUMP to dTMP. This methylation can be blocked by folate antagonists. We find that 5-fluo...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
1980
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6449701/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.10.6057 |
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