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The non-synonymous SNP, R1150W, in SCN9A is not associated with chronic widespread pain susceptibility

BACKGROUND: Mutations in SCN9A, encoding the alpha subunit of the voltage-gated sodium channel (Na(v)1.7), have caused severe pain disorders and congenital insensitivity to pain. The aim of this study was to validate the previously reported association between a common non-synonymous polymorphism (R...

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Detalhes bibliográficos
Main Authors: Holliday, Kate L, Thomson, Wendy, Neogi, Tuhina, Felson, David T, Wang, Ke, Wu, Frederick C, Huhtaniemi, Ilpo T, Bartfai, Gyorgy, Casanueva, Felipe, Forti, Gianni, Kula, Krzysztof, Punab, Margus, Vanderschueren, Dirk, Macfarlane, Gary J, Horan, Michael A, Ollier, William, Payton, Antony, Pendleton, Neil, McBeth, John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502104/
https://ncbi.nlm.nih.gov/pubmed/23006801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-72
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