The non-synonymous SNP, R1150W, in SCN9A is not associated with chronic widespread pain susceptibility

BACKGROUND: Mutations in SCN9A, encoding the alpha subunit of the voltage-gated sodium channel (Na(v)1.7), have caused severe pain disorders and congenital insensitivity to pain. The aim of this study was to validate the previously reported association between a common non-synonymous polymorphism (R...

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Библиографические подробности
Главные авторы: Holliday, Kate L, Thomson, Wendy, Neogi, Tuhina, Felson, David T, Wang, Ke, Wu, Frederick C, Huhtaniemi, Ilpo T, Bartfai, Gyorgy, Casanueva, Felipe, Forti, Gianni, Kula, Krzysztof, Punab, Margus, Vanderschueren, Dirk, Macfarlane, Gary J, Horan, Michael A, Ollier, William, Payton, Antony, Pendleton, Neil, McBeth, John
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2012
Предметы:
Short Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502104/
https://ncbi.nlm.nih.gov/pubmed/23006801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-72
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