The non-synonymous SNP, R1150W, in SCN9A is not associated with chronic widespread pain susceptibility

BACKGROUND: Mutations in SCN9A, encoding the alpha subunit of the voltage-gated sodium channel (Na(v)1.7), have caused severe pain disorders and congenital insensitivity to pain. The aim of this study was to validate the previously reported association between a common non-synonymous polymorphism (R...

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Autors principals: Holliday, Kate L, Thomson, Wendy, Neogi, Tuhina, Felson, David T, Wang, Ke, Wu, Frederick C, Huhtaniemi, Ilpo T, Bartfai, Gyorgy, Casanueva, Felipe, Forti, Gianni, Kula, Krzysztof, Punab, Margus, Vanderschueren, Dirk, Macfarlane, Gary J, Horan, Michael A, Ollier, William, Payton, Antony, Pendleton, Neil, McBeth, John
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502104/
https://ncbi.nlm.nih.gov/pubmed/23006801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-72
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