Regulation of insulin receptors: evidence for involvement of an endocytotic internalization pathway.

Cultured human fibroblasts degrade insulin by a receptor-mediated process. When intracellular hormone degradation is inhibited by chloroquine, 125I-labeled insulin internalizes and accumulates intracellularly. In contrast, cultured IM-9 lymphocytes do not degrade receptor-bound insulin or accumulate...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Baldwin, D, Prince, M, Marshall, S, Davies, P, Olefsky, J M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1980
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC350195/
https://ncbi.nlm.nih.gov/pubmed/6108561
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge