Regulation of insulin receptors: evidence for involvement of an endocytotic internalization pathway.

Cultured human fibroblasts degrade insulin by a receptor-mediated process. When intracellular hormone degradation is inhibited by chloroquine, 125I-labeled insulin internalizes and accumulates intracellularly. In contrast, cultured IM-9 lymphocytes do not degrade receptor-bound insulin or accumulate...

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Bibliografiska uppgifter

I publikationen:	Proc Natl Acad Sci U S A
Huvudupphov:	Baldwin, D, Prince, M, Marshall, S, Davies, P, Olefsky, J M
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	National Academy of Sciences 1980
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350195/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6108561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.10.5975
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