Chargement en cours...
Rapid, Microwave-Assisted Organic Synthesis of Selective (V600E)BRAF Inhibitors for Preclinical Cancer Research
We report a dramatically improved total synthesis of two highly selective (V600E)BRAF inhibitors, PLX4720 and PLX4032, that leverages microwave-assisted organic synthesis (MAOS). Compared with previously reported approaches, our novel MAOS method significantly reduces overall reaction time without c...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501741/ https://ncbi.nlm.nih.gov/pubmed/23180892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.05.137 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|