(18)F-FLT PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer

Selective inhibition of oncogenic targets and associated signaling pathways forms the basis of personalized cancer medicine. The clinical success of (V600E)BRAF inhibition in melanoma, coupled with the emergence of acquired resistance, underscores the importance of rigorously validating quantitative...

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Main Authors: McKinley, Eliot T., Smith, R. Adam, Zhao, Ping, Fu, Allie, Saleh, Samir A., Uddin, Imam, Washington, M. Kay, Coffey, Robert J., Manning, H. Charles
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633462/
https://ncbi.nlm.nih.gov/pubmed/23341544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.108456
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