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(18)F-FLT PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer

Selective inhibition of oncogenic targets and associated signaling pathways forms the basis of personalized cancer medicine. The clinical success of (V600E)BRAF inhibition in melanoma, coupled with the emergence of acquired resistance, underscores the importance of rigorously validating quantitative...

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Detalhes bibliográficos
Main Authors: McKinley, Eliot T., Smith, R. Adam, Zhao, Ping, Fu, Allie, Saleh, Samir A., Uddin, Imam, Washington, M. Kay, Coffey, Robert J., Manning, H. Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633462/
https://ncbi.nlm.nih.gov/pubmed/23341544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.108456
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