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Aging and the aggregating proteome

For all organisms promoting protein homeostasis is a high priority in order to optimize cellular functions and resources. However, there is accumulating evidence that aging leads to a collapse in protein homeostasis and widespread non-disease protein aggregation. This review examines these findings...

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Detalhes bibliográficos
Autor principal: David, Della C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501694/
https://ncbi.nlm.nih.gov/pubmed/23181070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00247
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