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Impairment of ribosomal subunit synthesis in aminoglycoside treated ribonuclease mutants of Escherichia coli
The bacterial ribosome is an important target for many antimicrobial agents. Aminoglycoside antibiotics bind to both 30S and 50S ribosomal subunits, inhibiting translation and subunit formation. During ribosomal subunit biogenesis, ribonucleases (RNases) play an important role in rRNA processing. E....
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501609/ https://ncbi.nlm.nih.gov/pubmed/22930249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00203-012-0839-5 |
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