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Impairment of ribosomal subunit synthesis in aminoglycoside treated ribonuclease mutants of Escherichia coli

The bacterial ribosome is an important target for many antimicrobial agents. Aminoglycoside antibiotics bind to both 30S and 50S ribosomal subunits, inhibiting translation and subunit formation. During ribosomal subunit biogenesis, ribonucleases (RNases) play an important role in rRNA processing. E....

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Библиографические подробности
Главные авторы: Frazier, Ashley D., Champney, W. Scott
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501609/
https://ncbi.nlm.nih.gov/pubmed/22930249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00203-012-0839-5
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