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Behavioral and electrophysiological outcomes of tissue-specific Smn knockdown in Drosophila melanogaster

Severe reduction in Survival Motor Neuron 1 (SMN1) protein in humans causes Spinal Muscular Atrophy (SMA), a debilitating childhood disease that leads to progressive impairment of the neuro-muscular system. Although previous studies have attempted to identify the tissue(s) in which SMN1 loss most cr...

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Detalhes bibliográficos
Main Authors: Timmerman, Christina, Sanyal, Subhabrata
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501589/
https://ncbi.nlm.nih.gov/pubmed/23103409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.10.035
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