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The Cytochrome b(5) dependent C-5(6) sterol desaturase DES5A from the endoplasmic reticulum of Tetrahymena thermophila complements ergosterol biosynthesis mutants in Saccharomyces cerevisiae

Tetrahymena thermophila is a free-living ciliate with no exogenous sterol requirement. However, it can perform several modifications on externally added sterols including desaturation at C5(6), C7(8), and C22(23). Sterol desaturases in Tetrahymena are microsomal enzymes that require Cyt b(5), Cyt b(...

詳細記述

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書誌詳細
主要な著者: Poklepovich, Tomas J., Rinaldi, Mauro A., Tomazic, Mariela L., Favale, Nicolas O., Turkewitz, Aaron P., Nudel, Clara B., Nusblat, Alejandro D.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501532/
https://ncbi.nlm.nih.gov/pubmed/22982564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2012.08.015
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