Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung

Despite their role in resolving inflammatory insults, neutrophils trigger inflammation-induced acute lung injury (ALI), culminating in acute respiratory distress syndrome (ARDS), a frequent complication with high mortality in humans. Molecular mechanisms underlying recruitment of neutrophils to site...

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Bibliographische Detailangaben
Hauptverfasser: Ittner, Arne, Block, Helena, Reichel, Christoph A., Varjosalo, Markku, Gehart, Helmuth, Sumara, Grzegorz, Gstaiger, Matthias, Krombach, Fritz, Zarbock, Alexander, Ricci, Romeo
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501357/
https://ncbi.nlm.nih.gov/pubmed/23129748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120677
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