Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis

Dysfunction and loss of insulin-producing pancreatic β cells represent hallmarks of diabetes mellitus. Here, we show that mice lacking the mitogen-activated protein kinase (MAPK) p38δ display improved glucose tolerance due to enhanced insulin secretion from pancreatic β cells. Deletion of p38δ resul...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sumara, Grzegorz, Formentini, Ivan, Collins, Stephan, Sumara, Izabela, Windak, Renata, Bodenmiller, Bernd, Ramracheya, Reshma, Caille, Dorothée, Jiang, Huiping, Platt, Kenneth A., Meda, Paolo, Aebersold, Rudolf, Rorsman, Patrik, Ricci, Romeo
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638021/
https://ncbi.nlm.nih.gov/pubmed/19135240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.11.018
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky