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NADPH Oxidase 1 Mediates α-Synucleinopathy in Parkinson's Disease

Accumulation of misfolded α-synuclein is the pathological hallmark of Parkinson's disease (PD). Nevertheless, little is known about the mechanism contributing to α-synuclein aggregation and its further toxicity to dopaminergic neurons. Since oxidative stress can increase the expression and aggr...

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Autors principals: Cristóvão, Ana Clara, Guhathakurta, Subhrangshu, Bok, Eugene, Je, Goun, Yoo, Seung Don, Choi, Dong-Hee, Kim, Yoon-Seong
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501265/
https://ncbi.nlm.nih.gov/pubmed/23077033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2246-12.2012
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