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Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate

[Image: see text] Bioluminescence methodologies have been extraordinarily useful due to their high sensitivity, broad dynamic range, and operational simplicity. These capabilities have been realized largely through incremental adaptations of native enzymes and substrates, originating from luminous o...

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Hlavní autoři: Hall, Mary P., Unch, James, Binkowski, Brock F., Valley, Michael P., Butler, Braeden L., Wood, Monika G., Otto, Paul, Zimmerman, Kristopher, Vidugiris, Gediminas, Machleidt, Thomas, Robers, Matthew B., Benink, Hélène A., Eggers, Christopher T., Slater, Michael R., Meisenheimer, Poncho L., Klaubert, Dieter H., Fan, Frank, Encell, Lance P., Wood, Keith V.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2012
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501149/
https://ncbi.nlm.nih.gov/pubmed/22894855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb3002478
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