Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate

[Image: see text] Bioluminescence methodologies have been extraordinarily useful due to their high sensitivity, broad dynamic range, and operational simplicity. These capabilities have been realized largely through incremental adaptations of native enzymes and substrates, originating from luminous o...

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Detalhes bibliográficos
Main Authors: Hall, Mary P., Unch, James, Binkowski, Brock F., Valley, Michael P., Butler, Braeden L., Wood, Monika G., Otto, Paul, Zimmerman, Kristopher, Vidugiris, Gediminas, Machleidt, Thomas, Robers, Matthew B., Benink, Hélène A., Eggers, Christopher T., Slater, Michael R., Meisenheimer, Poncho L., Klaubert, Dieter H., Fan, Frank, Encell, Lance P., Wood, Keith V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501149/
https://ncbi.nlm.nih.gov/pubmed/22894855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb3002478
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