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Orally Active Adenosine A(1) Receptor Agonists with Antinociceptive Effects in Mice

[Image: see text] Adenosine A(1) receptor (A(1)AR) agonists have antinociceptive effects in multiple preclinical models of acute and chronic pain. Although numerous A(1)AR agonists have been developed, clinical applications of these agents have been hampered by their cardiovascular side effects. Her...

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Detalhes bibliográficos
Main Authors: Korboukh, Ilia, Hull-Ryde, Emily A., Rittiner, Joseph E., Randhawa, Amarjit S., Coleman, Jennifer, Fitzpatrick, Brendan J., Setola, Vincent, Janzen, William P., Frye, Stephen V., Zylka, Mark J., Jin, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501123/
https://ncbi.nlm.nih.gov/pubmed/22738238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm3004834
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