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Prostatic Acid Phosphatase Is Required for the Antinociceptive Effects of Thiamine and Benfotiamine

Thiamine (Vitamin B1) is an essential vitamin that must be obtained from the diet for proper neurological function. At higher doses, thiamine and benfotiamine (S-benzoylthiamine O-monophosphate, BT)–a phosphorylated derivative of thiamine–have antinociceptive effects in animals and humans, although...

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Bibliographic Details
Main Authors: Hurt, Julie K., Coleman, Jennifer L., Fitzpatrick, Brendan J., Taylor-Blake, Bonnie, Bridges, Arlene S., Vihko, Pirkko, Zylka, Mark J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485352/
https://ncbi.nlm.nih.gov/pubmed/23119057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048562
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